Efficacy of the Whole Cell Vaccine Streptococcus agalactiae with Vector Artemia sp. for Streptococcosis Prevention in Nila Fish (Oreochromis niloticus)

This study aims to examine the efficacy of oral whole-cell vaccine S. agalactiae with Artemia sp as a vector for prevention against Streptococcosis in tilapia fish. The fish seeds used were 2-3 cm size which did not carry bacteria and reared jars volume 3 liters many ten birds/jar. Giving orally by first soaking sp. times 15, 30, 60, 90, 120 150 minutes. Parameters observed relative percent survival (RPS), antibody titer value, total leukocytes, phagocytic index, leukocyte differential. results showed that treatment between vaccines had no significant effect, while control effect (P<0.05). highest RPS value was obtained 30 minutes minutes, 93.33%. Furthermore, 86.67% at 15 80% soaking. shows level protection streptococcosis is very high.